ANTIARRHYTHMIC DRUGS

1. CLASS I: Membrane stabilizing agents (Na+ channel blockers)

a. Moderately decrease dv/dt of 0 phase

Quinidine

Procainamide

Disopyramide

Moricizine

b. Little decrease in dv/dt of 0 phase

Lidocaine

Mexiletine

c. Marked decrease in dv/dt of 0 phase

Propafenone

Flecainide

 

2. CLASS II: Antiadrenergic agents (β  blockers)

Propranolol

Esmolol

Sotalol (also class III)

3. CLASS III: Agents widening AP(prolong repolarization and ERP)

Amiodarone

Bretylium (also class II)

Dofetilide

Ibutilide

 

4. CLASS IV: Calcium channel blockers

Verapamil

Diltiazem

Additional antiarrhythmic drugs

a. For paroxysmal supraventricular tachycardia (PSVT):

Adenosine

Digitalis

b. For atrio-ventricular (A-V) block:

Sympathomimetics:

Isoprenaline, etc.

Anticholinergics:

Atropine