ANTIPARKINSONIAN DRUGS

1. DRUGS AFFECTING BRAIN DOPAMINERGIC SYSTEM

a. Dopamine precursor:

Levodopa

b. Peripheral decarboxylase inhibitors:

Carbidopa

Benserazide

c. Dopaminergic agonists:

Bromocriptine

Ropinirole

Pramipexole

d. MAO-B inhibitor:

Selegiline

e. COMT inhibitors:

Entacapone

Tolcapone

f. Glutamate(NMDA) agonist (Dopamine facilitator):

Amantadine

 

2. DRUGS AFFECTING BRAIN CHOLINERGIC SYSTEM

a. Central anticholinergics:

Trihexyphenidyl (Benzhexol)

Procyclidine

Biperiden

b. Antihistaminics:

Orphenadrine

Promethazine