CHOLINERGIC DRUGS

These are the drugs which produce actions same as acetylcholine, either by directly acting with cholinergic receptors or by increasing availability of Ach at the sites. They are also called as cholinomimetics or parasympathomimetics.

There are two types of Cholinergic drugs they are cholinergic agonists and anticholinesterases.

1. CHOLINERGIC AGONISTS

a) Choline esters:

Acetylcholine

Methacholine

Carbachol

Bethanechol

 

b)  Alkaloids:

Muscarine

Pilocarpine

Arecoline

 

2. ANTICHOLINESTERASES

a) Reversible

Carbamates:  

Physostigmine (Eserine)

Neostigmine

Pyridostigmine

Rivastigmine

Edrophonium

Donepezil

Galantamine

 

Acridine: 

Tacrine

 

b) Irreversible

Carbamates:

Carbaryl

Propoxur

 

Organophosphates:

Dyflos (DFP)

Echothiophate

Malathione

Diazinon

Tabun

Sarin

Soman

Isofluorophate