DIURETICS

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1. High efficacy diuretics (Inhibitors of Na+-K+-2Cl¯ cotransport)

a. Sulphamoyl derivatives:

Furosemide

Bumetanide

Torasemide

b. Phenoxyacetic acid derivative:

Ethacrynic acid

 

2. Medium efficacy diuretics (Inhibitors of Na+-Cl¯ symport)

a. Benzothiadiazines (thiazides):

Hydrochlorothiazide

Benzthiazide

Hydroflumethiazide

Clopamide

b. Thiazide like (related heterocyclics):

Chlorthalidone

Metolazone

Xipamide

Indapamide

 

3. Weak or adjunctive diuretics

a. Carbonic anhydrase inhibitors:

Acetazolamide

b. Potassium sparing diuretics:

    Aldosterone antagonist:

Spironolactone

Eplerenone

    Inhibitors of renal epithelial Na+ channel:

Triamterene

Amiloride

c. Osmotic diuretics:

Mannitol

Isosorbide

Glycerol

d. Xanthines:

Theophylline

 

 

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