VACCINES

VACCINES

 

1. Bacterial vaccines

    a. Killed (Inactivated)

                Typhoid-paratyphoid (TAB)

                Vi Typhoid polysaccharide (BCG)

                Cholera

                Whooping cough (Pertussis)

                Meningococcal

                Haemophilus influenzae  type B

                Plague

 

    b. Live attenuated

                Bacillus Calmette-Guérin (BCG)

                Typhoid-Ty 21a (Oral)

 

2. Viral vaccines

    a. Killed (Inactivated)

                Poliomyelitis inactivated (IPV, Salk)

                Rabies (Neural tissue)

                Rabies (Chick embryo cell, PCEV)

                Rabies (Human diploid cell, HDCV)

                Rabies (Vero cell, PVRV)

                Influenza

                Hepatitis B

                Hepatitis A

 

    b. Live attenuated

                Poliomyelitis oral live (OPV, Sabin)

                Mumps (live attenuated)

                Measles (live attenuated)

                Rubella (live attenuated)

                Varicella (live attenuated)

 

 

TOXOIDS

1. Tetanus (fluid/absorbed)

2. Diphtheria (absorbed)

 

 

COMBINED VACCINES

 

    Double antigen:

                Diphtheria toxoid + Tetanus toxoid (DT-DA)

 

    Triple antigen:

                Diphtheria toxoid + Tetanus toxoid + Pertussis vaccine (DPT)

 

    Pentavalent vaccine:

                DPT + Hepatitis B + Haemophilus influenzae  type B vaccines

 

    Others:

                Measles, mumps, rubella (MMR)

 

 

ANTISERA AND IMMUNEGLOBULINS

 

1. Antisera (from Horse)

                Tetanus antitoxin (ATS)

                Gas gangrene antitoxin (AGS)

                Diphtheria antitoxin (ADS)

                Antirabies serum (ARS)

                Antisnake venom polyvalent

 

2. Immune globins (Human)

                Normal human gamma globin

                Rho(D) immune globin

                Tetanus immune globin

                Rabies immune globin

                Hepatitis-B immune globin

ANTISEPTICS AND DISINFECTANTS

1. Phenol derivatives

Phenol

Cresol

Hexylresorcinol

Chloroxylenol

Hexachlorophene

 

2. Oxidizing agents

Potassium permanganate

Hydrogen peroxide

Benzoyl peroxide

 

3. Halogens

Iodine

Iodophores

Chlorine

Chlorophores

 

4. Biguanide

Chlorhexidine

 

5. Quaternary ammonium (Cationic)

Cetrimide

Benzalkonium chloride (Zephiran)

Dequalinium chloride

6. Soaps

Of Sodium and Potassium

 

7. Alcohols

Ethanol

Isopropanol

 

8. Aldehydes

Formaldehyde

Glutaraldehyde

 

9. Acids

Boric acid

Acetic acid

 

10. Metallic salts

Merbromin

Silver nitrate

Silver sulfadiazine

Mild silver protein

Zinc sulphate

Calamine

Zinc oxide

 

11. Dyes

Gentian violet

Brilliant green

Acriflavine

Proflavine

 

12. Furan derivative

Nitrofurazone

 

 

 

 

LOCALLY ACTING DRUGS ON SKIN AND MUCOUS MEMBRANES

1. Demulcents

Gum Acacia

Gum Tragacanth

Glycyrrhiza

Methylcellulose

Propylene glycol

Glycerine

 

2. Emollients

a. Vegetable oils:

Olive oil

Arachis oil

Sesame oil

Cocoa butter

b. Animal products:

Wool fat

Lard

Bees wax

Spermaceti

c. Petroleum products:

Paraffin wax (soft/hard)

Liquid paraffin

 

3. Adsorbants and Protectives

a. Dermal protectives:

Magnesium stearate

Zinc stearate

Talc

Calamine

Zinc oxide,

Bentonite

Starch

Boric acid

Aloe-vera gel

b. Occlusive protectives:

Polyvinyl polymer

Feracrylum

Dimethicone

Sucralfate

 

4. Astringents

a. Vegetable astringents:

Tannic acid: as glycerine of tannic acid 25%

Tannins: as tincture catechu, tea leaf infusion

b. Alcohols:

Ethanol

Methanol

Propanol

c. Mineral astringents:

Alum

Aluminium hydroxychloride

Zinc oxide

Zirconyl hydroxychloride

 

5. Counterirritants

a. Volatile  oils:

Turpentine oil

Eucalyptus oil

Clove oil

b. Stearoptenes:

Camphor

Thymol

Menthol

c. Other counterirritants:

Mustard seeds (as mustard plaster)

Capsicum

Canthridin

Methylsalicylate

Alcohol

 

6. Keratolytics and Caustics

Salicylic acid

Resorcinol

Podophyllum resin

Silver nitrate

Phenol

Trichloracetic acid

Glacial acetic acid

 

7. Antiseborrheics

 

Selenium sulphide

Zinc pyrithione

Sulfur

Resorcinol

Coal tar

Ketoconazole

Clotrimazole

Topical cortico-steroids

 

8. Melanizing agents

 

Psoralen

Methoxsalen

Trioxsalen

 

9. Demelanizing agents

Hydroquinone

Monobenzone

Azelaic acid

 

10. Sunscreens

a. Chemical sunscreens:

Para-aminobenzoic acid (PABA)

Oxybenzone

Octyl methoxy cinnamate

b. Physical sunscreens:

Petroleum jelly (heavy)

Titanium dioxide

Zinc oxide

Calamine

 

11. Drugs for Psoriasis

Topical corticosteroids

Calcipotriol

Tazarotene

Coaltar

Acitretin

Psoralen-ultraviolet A (PUVA) therapy

    Immunosuppressants:

Methotrexate

Etanercept

 

12. Drugs for Acne vulgaris

a. Topical therapy:

Antimicrobials:

Benzoyl peroxide

Erythromycin

Clindamycin

Nadifloxacin

Retinoids:

Tretinoin (Retinoic acid, all trans vitamin A acid)

Adapalene

Tazarotene

Others:

Azelaic acid

 

b. Systemic therapy:

Antibiotics:

Tetracycline

Minocycline

Erythromycin

Retinoid:

Isotretinoin (13-cis retinoic acid)

 

 

 

IMMUNOSUPPRESSANTS

1. Calcineurin inhibitors (Specific T-cell inhibitors)

Cyclosporine

Tacrolimus

2. m-TOR inhibitors

Sirolimus

Everolimus

3. Antiproliferative drugs (Cytotoxic drugs)

Azathioprine

Cyclophosphamide

Methotrexate

Chlorambucil

Mycophenolate mofetil (MMF), Sirolimus

 

4. Glucocorticoids

Prednisolone and others

 

5. Biological agents

a. TNFα  Inhibitors  

Etanercept

Infliximab

Adalimumab

b. IL-1 Receptor Antagonist

Anakinra

c. IL-2 Receptor Antagonist

Daclizumab

Basiliximab

d. Anti-CD3 Antibody

Muromonab CD3

e. Polyclonal Antibodies

Antithymocyte globulin (ATG), Rho(D) immuneglobulin

 

 

 

 

ANTICANCER DRUGS OR ANTINEOPLASTICS

DRUGS ACTING DIRECTLY ON CELLS (CYTOTOXIC DRUGS)

 

1. Alkylating Agents

a. Nitrogen mustards

Melphalan

Mechlorethamine (Mustine HCl)

Cyclophosphamide

Ifosfamide

Chlorambucil

b. Ethylenimine

Thio-TEPA

c. Alkyl sulfonate

Busulfan

d. Nitrosoureas

Carmustine

Lomustine

e. Triazine

Dacarbazine

Temozolomide

f. Methyl hydrazine

Procarbazine

 

2. Antimetabolites

a. Folate antagonist

Methotrexate

b. Purine Antagonist

6-Mercaptopurine

6-Thioguanine

Azathioprine

Fludarabine

c. PyrimidineAntagonist

5-Fluorouracil

Cytarabine

Capecitabine

 

3. Microtubule  Damaging Agents

a. Vinca alkaloids

Vincristine

Vinblastine

b. Taxanes

Paclitaxel

Docetaxel

c. Others

Estramustine

 

4. EpipodophylloToxin(Topoisomerase-2 inhibitor)

Etoposide

 

5. CamptothecinAnalogues (Topoisomerase-1 inhibitor)

Topotecan

Irinotecan

 

6. Antibiotics

Actinomycin D

Doxorubicin

Daunorubicin

Epirubicin

Mitoxantrone

Bleomycins

Mitomycin C

 

7. Miscellaneous

Hydroxyurea

L-Asparaginase

Tretinoin

Arsenic trioxide

 

 

 

TARGETED DRUGS

a. Tyrosine protein kinase inhibitors

Imatinib

Nilotinib

 

b. EGF receptor inhibitors

Gefitinib

Erlotinib

Cetuximab

 

c. Angiogenesis Inhibitors

Sunitinib

Bevacizumab

 

d. Proteosome inhibitor

Bortezomib

 

e. Monoclonal Antibody

Rituximab

 

 

DRUGS ALTERING HORMONAL MILIEU

 

1. Glucocorticoids

Prednisolone and others

 

2. Estrogens

Fosfestrol

Ethinylestradiol

 

3. Selective estrogen receptor modulators

Tamoxifen

Toremifene

 

4. Selective estrogen receptor down regulator

Fulvestrant

 

5. Aromatase inhibitors

Letrozole

Anastrozole

Exemestane

 

6. Antiandrogen

Flutamide

Bicalutamide

 

7. 5-α  reductase Inhibitors

Finasteride

Dutasteride

 

8. GnRH analogues

Naferelin

Triptorelin

 

9. Progestins

Hydroxyprogesterone caproate

 

 

 

ANTHELMINTICS

1. For Roundworm (Ascaris lumbricoides)

Mebendazole

Albendazole

Pyrantel

Piperazine

Levamisole

Ivermectin

2. For Hookworm (Ancylostoma duodenale, Necatoramericanus)

Mebendazole

Albendazole

Pyrantel

Levamisole

 

3. For Threadworm (Enterobius vermicularis)

Pyrantel

Mebendazole

Albendazole

Piperazine

4. For Strongyloides stercoralis

Ivermectin

Albendazole

 

5. For Whipworm (Trichuris trichiura)

Mebendazole

Albendazole

 

6. For Trichinella spiralis

Albendazole

Mebendazole

 

7. For Filariasis (Wuchereria bancrofti, Brugia malayi)

Diethyl carbamazine

Ivermectin

Albendazole

8. For Tapeworms (Taenia solium, T. saginata, Hymenolepisnana)

Praziquantel

Niclosamide

Albendazole

 

9. For Hydatid disease (Echinococcus granulosus, E.multilocularis)

Albendazole

Mebendazole

 

 

 

DRUGS FOR LEISHMANIASIS

1. Antimonials:

Sodium stibogluconate

Meglumine antimonite

 

2. Diamidine:

Pentamidine

 

3. Antifungal drugs:

Amphotericin B

Ketoconazole

 

4. Others:

Miltefosine

Paromomycin

Allopurinol

 

 

 

DRUGS FOR TRICHOMONIASIS

1. Drugs used orally

Metronidazole

Tinidazole

Secnidazole

Nimorazole

 

2. Drugs used intravaginally

Diiodohydroxyquin

Quiniodochlor

Clotrimazole

Metronidazole

Hamycin

Natamycin

Povidone-iodine