1. Gonadotropins are indicated in the following conditions except
A. Hypogonadotrophic hypogonadism in males
B. Cryptorchism in a boy less than 7 years old
C. Amenorrhoea and infertility in women
D. Polycystic ovaries
ANSWER: [ d ]
2. The hypothalamic gonadotropin releasing hormone (GnRH) is
A. A single peptide
B. A mixture of two distinct peptides FSH-RH and LH-RH
C. A mixture of several peptides
D. Dopamine
ANSWER: [ a ]
3. Menotropins is a preparation of
A. FSH + LH obtained from urine of menstruating women
B. LH obtained from urine of pregnant women
C. FSH + LH obtained from urine of menopausal women
D. LH obtained from serum of pregnant mare
ANSWER: [ c ]
4. Gynaecomastia can be treated with
A. Chlorpromazine
B. Cimetidine
C. Bromocriptine
D. Metoclopramide
ANSWER: [ c ]
5. The most prominent action of bromocriptine is
A. Dopamine D2 agonism
B. Dopamine D2 antagonism
C. Dopamine D1 antagonism
D. α adrenergic antagonism
ANSWER: [ a ]
6. Bromocriptine causes the following
A. Prolactin release
B. Vomiting
C. Uterine contraction
D. Impotence
ANSWER: [ b ]
7. Hyperprolactinemia can cause the following except
A. Amenorrhoea
B. Gynaecomastia
C. Multiple ovulation
D. Depressed fertility
ANSWER: [ c ]
8. For therapeutic use, growth hormone is obtained from
A. Recombinant DNA technique
B. Human cadaver pituitaries
C. Porcine pituitaries
D. Chemical synthesis
ANSWER: [ a ]
9. Drugs that suppress growth hormone release in acromegaly include the following except
A. Bromocriptine
B. Somatostatin
C. Octreotide
D. Nafarelin
ANSWER: [ d ]
10. Indications of somatostatin include
A. Macroprolactinoma
B. Zollinger Ellison syndrome
C. Bleeding esophageal varices
D. Steatorrhoea
ANSWER: [ c ]
11. Somatostatin inhibits the release of
A. Growth hormone
B. Insulin
C. Thyrotropin
D. All of the above
ANSWER: [ d ]
12. Octreotide is a long acting synthetic analogue of
A. Prolactin
B. Growth hormone
C. Somatostatin
D. Gonadotropin releasing hormone
ANSWER: [ c ]
13. Several actions of growth hormone are exerted through the elaboration of
A. Cyclic AMP
B. Cyclic GMP
C. Somatostatin
D. Insulin like growth factor-1
ANSWER: [ d ]
14. The following hypothalamic regulatory hormone is not a peptide
A. Growth hormone release inhibitory hormone
B. Prolactin release inhibitory hormone
C. Gonadotropin releasing hormone
D. Corticotropin releasing hormone
ANSWER: [ b ]
15. Which hormone acts through a cytoplasmic receptor
A. Calcitriol
B. Prolactin
C. Vasopressin
D. None of the above
ANSWER: [ a ]
16. Actions of growth hormone include the following except
A. Increased protein synthesis
B. Increased fat utilization
C. Increased carbohydrate utilization
D. Glucose intolerance
ANSWER: [ c ]